Maphula, A.Mashamba, T.Bessong, Pascal O.Takalani, Tanganedzani2019-10-222019-10-222019-09-20Takalani, Tanganedzani (2019) Adherence: Perceptions and behaviour of patients on Antiretroviral in Vhembe District of Limpopo Province, South Africa, University of Venda, South Africa.<http://hdl.handle.net/11602/1496>.http://hdl.handle.net/11602/1496MA (Psychology)Department of PsychologyBackground: An estimated 70% of people in Sub-Saharan Africa out of 25 million are living with HIV. HIV is a debilitating disease, however, antiretroviral treatment helps promote effective viral suppression, reduces the risk of transmission and prevents death (WHO, 2013). To ensure positive treatment outcomes, high levels of Anti-Retroviral Therapy (ART) adherence, 95%, is necessary, however, research indicates that 23% of Africans are achieving less than 80% adherence, potentially impacting negatively on prognosis. Aim: The aim of this study was to determine adherence, explore perceptions and behaviour of patients on Antiretroviral Therapy attending Thohoyandou Health Centre, in Vhembe District, Limpopo, South Africa. Methodology: This was a mixed method which employed both quantitative and qualitative research approaches. In quantitative, triangulation was utilised through a questionnaire and patients’ file, simple random sampling was used to select 105 male and female patients aged 18-60 who are on ART at Thohoyandou Health Centre; data were collected and SPSSversion 25 was used to analyse the data through descriptive, cross tabulation and inferential statistics using Chi-square.Qualitative phase – phenomelogical research design was utilised, twenty participants were purposively sampled and individually interviewed, ATLAS. ti program was used to analyse the data collected. Results: 67% of respondents were females, 34% of the respondents’ age range was 50-60 years, 44.8% were single, 48.6% had tertiary education and 69.5% were unemployed. The self-report of ART adherence of 87.6% among patients was indicated, with 19.6% who reported defaulting ART, 14.3% admitted to missing medical appointments. The reasons for missing medical appointments were: forgetfulness, not a convenient time, patient feeling better, transportation challenges and being too sick to attend. The objective evaluation of patients’ CD4 count at baseline revealed that 40.9% of patients had a CD4 count of <200c/mm3, out of 40.9% respondents (15.2%) were those aged between 41-50 years, 31.4% of respondents did not know their CD4 count for various reasons (defaulted on treatment, missed appointments). CD4 count follow-up data after six months revealed that 33% of patients had a CD4 count <200c/mm3 and 39% accounted for unknown CD4 count. vi Three themes emerged from the data, namely: Knowledge of HIV were respondents presented a negaitive and positive perception of ths diagnosis; barriers to ART adherence where sub-themes included discrimination, strigma, rejection, inadequate knowledge about the diagnosis and treatment, side effects; coping strategies where acceptance, religion and social support serve as corner stones for patients. Association was examined and findings did not reveal any significant association between gender, marital status, education, occupation; however, age was significantly associated with non-adherence to ART with X2 = 3.69, df = 1, p = < .002. Recommendations: The study recommends intensification of health education campaign against stigma, discrimination, rejection and other barriers to enhance positive attitude towards HIV patients that wil consequently stimulate adherence and alleviate the burden associated with taking treatment unswervingly. Given the high percentage of infected older respondents, government must also focus its resources to educate illiterate and older people about HIV, adherence and management in order to achieve the golden standardrate of 95% adherence. Strategies to facilitate and normalise adherence among males is indicated.1 online resource (xxii, 138 leaves: illustrations, color map)enUniversity of VendaAcquired Immune Deficiency Syndrome (AIDS)UCTDAdherenceAnti-retroviral therapy /treatment (ARI)Human Immunodefiency Virus (HIV)PatientsPerceptionsBehaviour616.979200968257HIV (Viruses) -- South Africa -- LimpopoHTLV (Viruses) -- South Africa -- LimpopoVirus-induced immunosuppression -- South Africa -- LimpopoAIDS (Disease) -- South Africa -- LimpopoAIDS (Disease) -- Patients -- South Africa -- LimpopoHIV-positive persons -- South Africa -- LimpopoAdherence: Perceptions and behaviour of patients on Antiretroviral in Vhembe District of Limpopo Province, South AfricaDissertationTakalani T. Adherence: Perceptions and behaviour of patients on Antiretroviral in Vhembe District of Limpopo Province, South Africa. []. , 2019 [cited yyyy month dd]. Available from: http://hdl.handle.net/11602/1496Takalani, T. (2019). <i>Adherence: Perceptions and behaviour of patients on Antiretroviral in Vhembe District of Limpopo Province, South Africa</i>. (). . Retrieved from http://hdl.handle.net/11602/1496Takalani, Tanganedzani. <i>"Adherence: Perceptions and behaviour of patients on Antiretroviral in Vhembe District of Limpopo Province, South Africa."</i> ., , 2019. http://hdl.handle.net/11602/1496TY - Dissertation AU - Takalani, Tanganedzani AB - Background: An estimated 70% of people in Sub-Saharan Africa out of 25 million are living with HIV. HIV is a debilitating disease, however, antiretroviral treatment helps promote effective viral suppression, reduces the risk of transmission and prevents death (WHO, 2013). To ensure positive treatment outcomes, high levels of Anti-Retroviral Therapy (ART) adherence, 95%, is necessary, however, research indicates that 23% of Africans are achieving less than 80% adherence, potentially impacting negatively on prognosis. Aim: The aim of this study was to determine adherence, explore perceptions and behaviour of patients on Antiretroviral Therapy attending Thohoyandou Health Centre, in Vhembe District, Limpopo, South Africa. Methodology: This was a mixed method which employed both quantitative and qualitative research approaches. In quantitative, triangulation was utilised through a questionnaire and patients’ file, simple random sampling was used to select 105 male and female patients aged 18-60 who are on ART at Thohoyandou Health Centre; data were collected and SPSSversion 25 was used to analyse the data through descriptive, cross tabulation and inferential statistics using Chi-square.Qualitative phase – phenomelogical research design was utilised, twenty participants were purposively sampled and individually interviewed, ATLAS. ti program was used to analyse the data collected. Results: 67% of respondents were females, 34% of the respondents’ age range was 50-60 years, 44.8% were single, 48.6% had tertiary education and 69.5% were unemployed. The self-report of ART adherence of 87.6% among patients was indicated, with 19.6% who reported defaulting ART, 14.3% admitted to missing medical appointments. The reasons for missing medical appointments were: forgetfulness, not a convenient time, patient feeling better, transportation challenges and being too sick to attend. The objective evaluation of patients’ CD4 count at baseline revealed that 40.9% of patients had a CD4 count of <200c/mm3, out of 40.9% respondents (15.2%) were those aged between 41-50 years, 31.4% of respondents did not know their CD4 count for various reasons (defaulted on treatment, missed appointments). CD4 count follow-up data after six months revealed that 33% of patients had a CD4 count <200c/mm3 and 39% accounted for unknown CD4 count. vi Three themes emerged from the data, namely: Knowledge of HIV were respondents presented a negaitive and positive perception of ths diagnosis; barriers to ART adherence where sub-themes included discrimination, strigma, rejection, inadequate knowledge about the diagnosis and treatment, side effects; coping strategies where acceptance, religion and social support serve as corner stones for patients. Association was examined and findings did not reveal any significant association between gender, marital status, education, occupation; however, age was significantly associated with non-adherence to ART with X2 = 3.69, df = 1, p = < .002. Recommendations: The study recommends intensification of health education campaign against stigma, discrimination, rejection and other barriers to enhance positive attitude towards HIV patients that wil consequently stimulate adherence and alleviate the burden associated with taking treatment unswervingly. Given the high percentage of infected older respondents, government must also focus its resources to educate illiterate and older people about HIV, adherence and management in order to achieve the golden standardrate of 95% adherence. Strategies to facilitate and normalise adherence among males is indicated. DA - 2019-09-20 DB - ResearchSpace DP - Univen KW - Acquired Immune Deficiency Syndrome (AIDS) KW - Adherence KW - Anti-retroviral therapy /treatment (ARI) KW - Human Immunodefiency Virus (HIV) KW - Patients KW - Perceptions KW - Behaviour LK - https://univendspace.univen.ac.za PY - 2019 T1 - Adherence: Perceptions and behaviour of patients on Antiretroviral in Vhembe District of Limpopo Province, South Africa TI - Adherence: Perceptions and behaviour of patients on Antiretroviral in Vhembe District of Limpopo Province, South Africa UR - http://hdl.handle.net/11602/1496 ER -