Ledwaba, S. E.Kabue, J. P.Barnard, T. G.Traore, A. N.Potgieter, N.2022-11-092022-11-092018-06-18Ledwaba, S. E., Kabue, J. P., Barnard, T. G., Traore, A. N. and Potgieter, N. Enteric pathogen co-infections in the paediatric population from rural communities in the Vhembe District, South Africa.S Afr J Child Health 2018;12(4):170-174. DOI:10.7196/SAJCH.2018.v12.i4.1550.<http://hdl.handle.net/11602/2334>.DOI:10.7196/SAJCH.2018.v12.i4.1550.http://hdl.handle.net/11602/2334Background. Enteric pathogens co-infections are a serious health risk in children under the age of 5 years. Objective. The study aimed to determine the prevalence of diarrhoea-causing pathogens in children suffering from diarrhoea in rural communities of the Vhembe District. Methods. A cross-sectional study was conducted from July 2014 to June 2015. Diarrhoeal stool specimens (N=237) were collected from children attending primary healthcare facilities in rural communities of the Vhembe District. Stools were screened for enteric viral adenovirus 40/41, rotavirus and norovirus pathogens by means of enzyme immuno-assay (EIA) and enteric bacterial Escherichia coli spp. (diarrhoeagenic pathotypes), Shigella spp., Salmonella spp. and Vibrio spp. pathogens by means of multiplex polymerase chain reaction. Results. A total of 59.1% (140/237) were positive for at least one or more enteric pathogens. Enterotoxigenic E. coli (ETEC) (27.9%), enteroaggregative E. coli (EAEC) (26.8%) and atypical enteropathogenic E. coli (EPEC) (17.9%) were frequently detected in children less than 2 years of age. Bacterial-bacteria co-infections were detected in 24.5% (n=58) and bacterial-viral co-infections in 14.3% (n=34) of the stool specimens. Conclusion. The findings indicated that enteric pathogen co-infections are major causes of diarrhoea in children less than 2 years of age in the Vhembe District.enUCTDArticleLedwaba S E, Kabue J P, Barnard T G, Traore A N, Potgieter N. Enteric pathogen co-infections in the paediatric population from rural communities in the Vhembe District, South Africa. 2018; http://hdl.handle.net/11602/2334.Ledwaba, S. E., Kabue, J. P., Barnard, T. G., Traore, A. N., & Potgieter, N. (2018). Enteric pathogen co-infections in the paediatric population from rural communities in the Vhembe District, South Africa. http://hdl.handle.net/11602/2334Ledwaba, S. E., J. P. Kabue, T. G. Barnard, A. N. Traore, and N. Potgieter "Enteric pathogen co-infections in the paediatric population from rural communities in the Vhembe District, South Africa." (2018) http://hdl.handle.net/11602/2334TY - Article AU - Ledwaba, S. E. AU - Kabue, J. P. AU - Barnard, T. G. AU - Traore, A. N. AU - Potgieter, N. AB - Background. Enteric pathogens co-infections are a serious health risk in children under the age of 5 years. Objective. The study aimed to determine the prevalence of diarrhoea-causing pathogens in children suffering from diarrhoea in rural communities of the Vhembe District. Methods. A cross-sectional study was conducted from July 2014 to June 2015. Diarrhoeal stool specimens (N=237) were collected from children attending primary healthcare facilities in rural communities of the Vhembe District. Stools were screened for enteric viral adenovirus 40/41, rotavirus and norovirus pathogens by means of enzyme immuno-assay (EIA) and enteric bacterial Escherichia coli spp. (diarrhoeagenic pathotypes), Shigella spp., Salmonella spp. and Vibrio spp. pathogens by means of multiplex polymerase chain reaction. Results. A total of 59.1% (140/237) were positive for at least one or more enteric pathogens. Enterotoxigenic E. coli (ETEC) (27.9%), enteroaggregative E. coli (EAEC) (26.8%) and atypical enteropathogenic E. coli (EPEC) (17.9%) were frequently detected in children less than 2 years of age. Bacterial-bacteria co-infections were detected in 24.5% (n=58) and bacterial-viral co-infections in 14.3% (n=34) of the stool specimens. Conclusion. The findings indicated that enteric pathogen co-infections are major causes of diarrhoea in children less than 2 years of age in the Vhembe District. DA - 2018-06-18 DB - ResearchSpace DP - Univen LK - https://univendspace.univen.ac.za PY - 2018 T1 - Enteric pathogen co-infections in the paediatric population from rural communities in the Vhembe District, South Africa TI - Enteric pathogen co-infections in the paediatric population from rural communities in the Vhembe District, South Africa UR - http://hdl.handle.net/11602/2334 ER -