BACKGROUND: Child daycare centers (DCCs) host a variety of pathogenic enteric microorganisms which may be found in various areas within the compound. Enteric pathogens are the most common cause of diarrhoea worldwide in ...
Background: Acute gastroenteritis (AGE) is a major cause of morbidity and mortality in children globally. Several reports have indicated that diarrheal diseases caused by viruses, bacteria and parasites are associated with ...
Background: Plant-derived natural products continue to serve as a reservoir for the discovery of new medicines. In South Africa, the use of plants to treat many diseases is widely practiced. This is due to high cost of ...
Background: Amebiasis is a common parasitic disease that contributes to the burden of diarrhea in areas with poor sanitation and inadequate water supply worldwide. Water quality, therefore, plays an essential role in the ...
Background: Globally, approximately 7,600,000 children under the age of 5 die annually due to diarrhea caused by viruses, bacteria and parasites. Human Astrovirus (HAstVs) has been identified as a causative agent of diarrheal ...
Background: Staphylococcus species and Eschericia Coli has been predominantly found to cause mastitis in dairy farms. Milk harbor various pathogenic microorganisms that causes foodborne and intramammary infections. The aim ...
Diarrhoea is still a major problem worldwide. Enteric pathogens such as Enteroaggregative E. coli (EAEC), Enteropathogenic E. coli (EPEC) and Enterotoxigenic E. coli (ETEC) have been reported to cause diarrhoea in children ...
Background: Escherichia coli is a facultative anaerobic bacterium that forms part of
the gut microbiota. It is used as an indicator that confirms recent faecal contamination.
E. coli have been identified amongst the ...
Background: Patients on antiretroviral (ART) are expected to be at least 95% adherent to their treatment, as this will increase their chances of achieving treatment success (maximum and durable suppression of HIV-1 viral ...
Background Conversion of Cholesterol to 25-HydroxyCholesterol (25HC) by Cholesterol
25-hydroxylase (CH25H) has been shown to exert broad antiviral properties. Given its
antiviral activities, CH25H is part of an increasingly ...
High genetic diversity is a major contributory factor in the development of drug resistance, in
addition to challenges in diagnosis and treatment monitoring in the therapeutics of human
immunodeficiency virus (HIV) .Within ...
Background: Currently, Human Immunodeficiency Virus/ Acquired Immune Deficiency
Syndrome (HIV/AIDS) is one of the deadliest diseases in the world. In Gabon, the prevalence
is estimated at 4.1%. Because of the several ...
The importance of traditional medicine has been recorded throughout the world. It has also been practiced throughout Africa by more than 80 % of rural communities. Traditional medicine has since been imbedded in the culture ...
Bessong, Pascal O.; Rojas, Luis B; Obi, Larry C.; Tshisikhawe, Peter M.; Igunbor, Eunice O.(2006-03-15)
The use of medicinal plants for AIDS-related conditions is common in South Africa. In order to establish
an antiviral rationale for the use of these plants we screened fractions of the methanol extracts of
medicinal ...
BACKGROUND: Human papillomavirus (HPV) is a common sexually transmitted virus known to be a causative agent of cervical cancer (CC), one of the most frequent cancers in women worldwide. HPV is a double stranded DNA virus ...
Sigidi, M. T.; Anokwuru, C. P.; Zininga, T.; Tshisikhawe, M. P.; Shonhai, A.; Ramaite, I. D. I.; Traore, A. N.; Potgieter, N.(BioMed Central, 2016 Decem)
Background: The Vhembe region of the Limpopo province has a rich tradition of medicinal plants use. Traditionally,
boiled roots of Ziziphus mucronata are used in the treatment of boils, general swelling and other skin ...
BACKGROUND: Human norovirus (NoV) is the etiological agent associated with acute gastroenteritis (AGE) in both children and adults worldwide. Children of <5 years of age, the elderly and individuals suffering from chronic ...
Background: The high on-going incidences of infectious diseases, specifically those caused by multi-drug resistant bacteria in the last decade has made it a necessity to investigate a variety of antimicrobial drug sources, ...
Background: Antiretroviral treatment (ART) has grown to be one of the most effective
tool in the fight to control HIV/AIDS morbidity and mortality worldwide. However, due to
the emergence of drug resistant HIV, ART ...
Background: The occurrence of microorganisms and endocrine disrupting chemicals
(EDCs) in water poses a serious concern due to their effects on humans, animals and
environment. In recent years, EDCs have been increasingly ...