BACKGROUND: Child daycare centers (DCCs) host a variety of pathogenic enteric microorganisms which may be found in various areas within the compound. Enteric pathogens are the most common cause of diarrhoea worldwide in ...
Glioblastoma multiforme (GBM) is the deadliest brain tumour. GBM is associated with poor prognosis, with its patients having a very short median survival and poor response to chemotherapy. GBM is a World Health Organization ...
Malaria is caused by protozoan parasites of the Plasmodium genus. An estimated 405 000 million deaths due to malaria were reported in 2018. Plasmodium falciparum (P. falciparum) accounts for the deadliest form of the disease ...
Adsorption of Coomassie brilliant blue (CBB G-250) from aqueous solutions on the adsorbents chitosan, alpha cellulose, banana rachis fibre, banana rachis fibre/chitosan composite, alpha cellulose/chitosan composite, and ...
The main malaria agent, Plasmodium falciparum, exhibits a complex life cycle. The parasite initially develops in a poikilothermic mosquito vector before it is subsequently transmitted to a homeothermic human host. As such, ...
Background: Acute gastroenteritis (AGE) is a major cause of morbidity and mortality in children globally. Several reports have indicated that diarrheal diseases caused by viruses, bacteria and parasites are associated with ...
Background: Plant-derived natural products continue to serve as a reservoir for the discovery of new medicines. In South Africa, the use of plants to treat many diseases is widely practiced. This is due to high cost of ...
Background: Amebiasis is a common parasitic disease that contributes to the burden of diarrhea in areas with poor sanitation and inadequate water supply worldwide. Water quality, therefore, plays an essential role in the ...
Background: Globally, approximately 7,600,000 children under the age of 5 die annually due to diarrhea caused by viruses, bacteria and parasites. Human Astrovirus (HAstVs) has been identified as a causative agent of diarrheal ...
Background: Staphylococcus species and Eschericia Coli has been predominantly found to cause mastitis in dairy farms. Milk harbor various pathogenic microorganisms that causes foodborne and intramammary infections. The aim ...
Diarrhoea is still a major problem worldwide. Enteric pathogens such as Enteroaggregative E. coli (EAEC), Enteropathogenic E. coli (EPEC) and Enterotoxigenic E. coli (ETEC) have been reported to cause diarrhoea in children ...
In 2017 malaria cases were estimated at 219 million and of these 435 000 resulted in death. Malaria is transmitted by female Anopheles mosquitoes which thrive in tropical and sub-tropical areas. Malaria is caused by five ...
Background: Escherichia coli is a facultative anaerobic bacterium that forms part of
the gut microbiota. It is used as an indicator that confirms recent faecal contamination.
E. coli have been identified amongst the ...
Background: Patients on antiretroviral (ART) are expected to be at least 95% adherent to their treatment, as this will increase their chances of achieving treatment success (maximum and durable suppression of HIV-1 viral ...
Background Conversion of Cholesterol to 25-HydroxyCholesterol (25HC) by Cholesterol
25-hydroxylase (CH25H) has been shown to exert broad antiviral properties. Given its
antiviral activities, CH25H is part of an increasingly ...
The main malaria agent, Plasmodium falciparum expresses an Hsp70 (PfHsp70-1) which plays a significant role in parasite survival. PfHsp70-1 is distinct in that it possesses glycine-glycine-methionine-proline (GGMP) ...
High genetic diversity is a major contributory factor in the development of drug resistance, in
addition to challenges in diagnosis and treatment monitoring in the therapeutics of human
immunodeficiency virus (HIV) .Within ...
Background: Currently, Human Immunodeficiency Virus/ Acquired Immune Deficiency
Syndrome (HIV/AIDS) is one of the deadliest diseases in the world. In Gabon, the prevalence
is estimated at 4.1%. Because of the several ...
BACKGROUND: Human papillomavirus (HPV) is a common sexually transmitted virus known to be a causative agent of cervical cancer (CC), one of the most frequent cancers in women worldwide. HPV is a double stranded DNA virus ...
BACKGROUND: Human norovirus (NoV) is the etiological agent associated with acute gastroenteritis (AGE) in both children and adults worldwide. Children of <5 years of age, the elderly and individuals suffering from chronic ...