Objective: The development of HIV drug resistance is a significant challenge in maintaining suppressed viral load in the management of patients. Next generation sequencing (NGS) is a more sensitive approach to determine ...
Adsorption of Coomassie brilliant blue (CBB G-250) from aqueous solutions on the adsorbents chitosan, alpha cellulose, banana rachis fibre, banana rachis fibre/chitosan composite, alpha cellulose/chitosan composite, and ...
BACKGROUND: Human papillomavirus (HPV) is a common sexually transmitted virus known to be a causative agent of cervical cancer (CC), one of the most frequent cancers in women worldwide. HPV is a double stranded DNA virus ...
Background: Amebiasis is a common parasitic disease that contributes to the burden of diarrhea in areas with poor sanitation and inadequate water supply worldwide. Water quality, therefore, plays an essential role in the ...
BACKGROUND: Human norovirus (NoV) is the etiological agent associated with acute gastroenteritis (AGE) in both children and adults worldwide. Children of <5 years of age, the elderly and individuals suffering from chronic ...
For decades, plants have been the backbone of complicated traditional herbal medicine system. Plants have been used by people and animals as a source of nutrients as well as medicine. Production of secondary metabolites ...
Background: Prostate cancer (PCA) is a major health concern in males, particularly those above 40 years old. It is the most common form of cancer in males worldwide, including South Africa. In South Africa, the rate of ...
Malaria is caused by protozoan parasites of the Plasmodium genus. An estimated 405 000 million deaths due to malaria were reported in 2018. Plasmodium falciparum (P. falciparum) accounts for the deadliest form of the disease ...
Background: Diarrheal diseases have a major effect on human health, Globally; it is
second only to pneumonia as a leading cause of death among children under five.
They are due to a variety of infectious and non-infectious ...
Hsp70 is a prominent molecular chaperone. Structurally, Hsp70 is composed of two domains,
C-terminus substrate binding domain (SBD) and nucleotide binding domain (NBD). The NBD
of Hsp70 is responsible for its ATPase ...
Background: Tuberculosis (TB) is implausibly still considered as one of the leading causes
of death, in the 21st century. Despite the curative treatments and measures of control in the
communities, TB plays a significant ...
Medicinal plants play an important role in both health and the livelihood of people. These plants have been used for medicinal purposes since time memorial, and they are deemed safer than their synthetic counterparts. One ...
Background: Currently, Human Immunodeficiency Virus/ Acquired Immune Deficiency
Syndrome (HIV/AIDS) is one of the deadliest diseases in the world. In Gabon, the prevalence
is estimated at 4.1%. Because of the several ...
In 2017 malaria cases were estimated at 219 million and of these 435 000 resulted in death. Malaria is transmitted by female Anopheles mosquitoes which thrive in tropical and sub-tropical areas. Malaria is caused by five ...
The main malaria agent, Plasmodium falciparum expresses an Hsp70 (PfHsp70-1) which plays a significant role in parasite survival. PfHsp70-1 is distinct in that it possesses glycine-glycine-methionine-proline (GGMP) ...