Browsing Department of Biochemistry and Microbiology by Subject "PfHsp40"

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Characterization of Plasmodium falciparum PFF1010c and screening of pyrimidine-quinoline hybrids as inhibitors of HsP70-HsP40 functional partnerships of the Malaria parasite

Mudau, Pertunia Thendo (2021-05)

With nearly half the world’s population at risk of malaria infection, 229 million new cases were recorded in 2019 with Sub-Saharan Africa accounting for most of these cases. In 2020, 384 000 malaria deaths were reported ...
Comparative analysis of a chimeric Hsp70 of E. coli and Plasmodium falciparum origin relative to its wild type forms

Lebepe, Charity Mekgwa (2019-05-18)

Sustaining proteostasis is essential for the survival of the cell and altered protein regulation leads to many cellular pathologies. Heat shock proteins (Hsps) are involved in the regulation of the protein quality control. ...

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