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Browsing Natural and Mathematical Sciences Departments by Author "Shonhai, Addmore"

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Characterization of heat shock protein 70-z (PfHsp70-z) from plasmodium falciparium

Zininga, Tawanda (2015)

Malaria is a parasitic disease that accounts for more than 660 thousand deaths annually, mainly in children. Malaria is caused by five Plasmodium species P. ovale, P. vivax, P. malariae, P. falciparum and P. knowlesi. ...
Extracts Obtained from Pterocarpus angolensis DC and Ziziphus mucronata Exhibit Antiplasmodial Activity and Inhibit Heat Shock Protein 70 (Hsp70) Function

Zininga, Tawanda; Anokwuru, Chineda P.; Sigidi, Muendi T.; Tshisikhawe, Milingoni P.; Ramaite, Isaiah I. D.; Traore, Afsatou N.; Hoppe, Heinrich; Shonhai, Addmore; Potgieter, Natasha (MDPI, 2017)

Malaria parasites are increasingly becoming resistant to currently used antimalarial therapies, therefore there is an urgent need to expand the arsenal of alternative antimalarial drugs. In addition, it is also important ...
Overexpression and structure-function characterization of HIV-1 Subtype C. reverse transcriptase and protease

Tambani, Tshifhiwa (2019-09-20)

High genetic diversity is a major contributory factor in the development of drug resistance, in addition to challenges in diagnosis and treatment monitoring in the therapeutics of human immunodeficiency virus (HIV) .Within ...
The Presence of Toxic and Non-Toxic Cyanobacteria in the Sediments of the Limpopo River Basin: Implications for Human Health

Magonono, Murendeni; Oberholster, Paul Johan; Shonhai, Addmore; Makumire, Stanley; Gumbo, Jabulani Ray (MDPI, 2018-07-03)

The presence of harmful algal blooms (HABs) and cyanotoxins in drinking water sources poses a great threat to human health. The current study employed molecular techniques to determine the occurrence of non-toxic and ...
The role of molecular chaperones in Escherichia coli cells subjected to gold nanoparticles induced stress

Mathomu, Lutendo Michael (2022-07-15)

Colloidal suspensions of gold particles of nanometre (nm) sizes are termed gold nanoparticles (AuNPs). Although stable, AuNPs have been reported to be toxic to E. coli cells by collapsing the bacterial cell membranes and ...

Browsing Natural and Mathematical Sciences Departments by Author "Shonhai, Addmore"

Browsing Natural and Mathematical Sciences Departments by Author "Shonhai, Addmore"

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