• Investigation of the role of HSP70 in the uptake of Granzyme B by Malaria parasite-infected erythrocytes 

  Ramatsui, Lebogang (2019-09-20)

  In 2017 malaria cases were estimated at 219 million and of these 435 000 resulted in death. Malaria is transmitted by female Anopheles mosquitoes which thrive in tropical and sub-tropical areas. Malaria is caused by five ...
• AB INITIO and DFT computational study of Myristinin A and A structurally- related molecule 

  Tshilande, Neani (2019-09-20)

  The computational study of biologically active molecules is particularly important for drug development because it provides crucial information about the properties of a molecule, which determine its biological activities. ...
• Method development for the determination of residual pesticides and heavy metals in complex samples using modern preconcentration techniques 

  Musarurwa, Herbert (2019-09-20)

  In this work, modern pre-concentration techniques, namely dispersive liquid-liquid micro-extraction (DLLME) and QuEChERS, were used to analyse pesticides and heavy metals in complex matrices. The work is divided into six ...
• A comparison of some methods of modeling baseline hazard function in discrete survival models 

  Mashabela, Mahlageng Retang (2019-09-20)

  The baseline parameter vector in a discrete-time survival model is determined by the number of time points. The larger the number of the time points, the higher the dimension of the baseline parameter vector which often ...
• Characterization of E. coli strains from rural communities in the Vhembe District (Limpopo South Africa) 

  Banda, Ntshunxeko Thelma (2019-09-20)

  Background: Escherichia coli is a facultative anaerobic bacterium that forms part of the gut microbiota. It is used as an indicator that confirms recent faecal contamination. E. coli have been identified amongst the ...
• Evaluation of adherence to antiretroviral therapy using efarivenz as a marker 

  Tambe, Lisa Arrah Mbang (2019-09-20)

  Background: Patients on antiretroviral (ART) are expected to be at least 95% adherent to their treatment, as this will increase their chances of achieving treatment success (maximum and durable suppression of HIV-1 viral ...
• Ethnomedicinal survey of invasive alien plant species used in the Capricorn District, Limpopo Province, South Africa 

  Cherane, Mosibudi Wendy (2019-09-20)

  Invasive alien plants (IAPs) are non-native species that have spread beyond the introduction site; become abundant to an extent that they serve as agents of change that also threaten native biological diversity ...
• Studies of interaction of dye molecules with TiO2 Brookite clusters for application in dye sensitized solar cells 

  Elegbeleye, Ife Fortunate (2019-09-20)

  Dye sensitized solar cells (DSSCs) have attracted rapid interest over the recent years with prospect of emerging as a viable alternative to conventional silicon based solar cells. The photoanode of DSSCs comprises of dye ...
• The ethnobotanical investigation of the Mapulana of Ehlanzeni District Municipality, Mpumalanga Province, South Africa 

  Mashile, Shalom Pabalelo (2019-09-20)

  Ethnobotanical information still needs documentation as this will assist in the preservation of information for future generation. It becomes most important, particularly when considering the neglected ethnic subgroups. ...
• Characterization of cholesterol 25-hydroxylase expression in human macrophages 

  Magoro, Tshifhiwa (2019-09-20)

  Background Conversion of Cholesterol to 25-HydroxyCholesterol (25HC) by Cholesterol 25-hydroxylase (CH25H) has been shown to exert broad antiviral properties. Given its antiviral activities, CH25H is part of an increasingly ...
• Evaluation of the regression coefficients for South Africa from solar radiation data 

  Mulaudzi, Tshimangadzo Sophie (2019-09-20)

  The knowledge of solar radiation in this dispensation is crucial. The lack of grid lines in the remote rural areas of South Africa necessitates the use of solar energy as an alternative energy resource. Solar radiation ...
• Conservation Strategies of the Red Listed Brackenridgea zanguebarica Oliv. in Vhembe District Municipality, Limpopo Province, South Africa 

  Tiawoun, Makuete Andre (2019-09-20)

  Brackenridgea zanguebarica Oliv. (Ochnaceae) commonly known as “Yellow Peeling Plane”, is an important medicinal plant species, and one of the most threatened tree species that is endemic to Thengwe village in Vhembe ...
• Isolation and characterization of antidiabetic constituents of Bridelia Micrantha 

  Maluleke, Khanyisa Amanda (2019-08-20)

  Bridelia micrantha (Hochst) Baill (B. micrantha) is a South African medicinal plant used by traditional healers in the treatment of different human ailments including diabetes, gastrointestinal ailments, joint aches, cough, ...
• Multi-elemental analysis of heavy metals present in dust emitted from cement plants located in Pretoria and Thabazimbi, South Africa 

  Matodzi, Vhahangwele (2019-09-20)

  Increasing health and environmental concern about the effects of most toxic heavy metals emitted from cement plants in developing countries, which are going through rapid development, has led to this study. Cement industry ...
• Understanding spatial structuring and the role of domestication in the development of sustainable harvest techniques of Mopane worms (Gonimbrasia belina). 

  Nethanani, Zwannda (2019-09-20)

  Mopane worm (Gonimbrasia belina Westwood) is an indigenous edible insect that periodically has population eruptions in Mopane tree (Colosphermum mopane) dominated vegetation. This insect is a valuable source of food and ...
• Isolation, characterisation and antimalarial activity of four selected South African plants 

  Adebayo, Oluwakemi Monisola (2019-09-20)

  Malaria, an infectious disease affecting both human beings and other animals, is transmitted by parasitic protozoans belonging to the Plasmodium genus. Malaria is commonly treated with drugs such as quinine, chloroquine, ...
• Investigation of the role of the GGMP motif of Plasmodium falciparum Hsp70-1 on the chaperone function of the protein and its interaction with a co-chaperone, PfHop 

  Makumire, Stanley (2019-09-20)

  The main malaria agent, Plasmodium falciparum expresses an Hsp70 (PfHsp70-1) which plays a significant role in parasite survival. PfHsp70-1 is distinct in that it possesses glycine-glycine-methionine-proline (GGMP) ...
• Recent numerical techniques for differential equations arising in fluid flow problems 

  Muzara, Hillary (2019-09-20)

  The work presented in this thesis is the application of the recently introduced numerical techniques, namely the spectral quasi-linearization method (SQLM) and the bivariate spectral quasi-linearization method (BSQLM), ...
• Overexpression and structure-function characterization of HIV-1 Subtype C. reverse transcriptase and protease 

  Tambani, Tshifhiwa (2019-09-20)

  High genetic diversity is a major contributory factor in the development of drug resistance, in addition to challenges in diagnosis and treatment monitoring in the therapeutics of human immunodeficiency virus (HIV) .Within ...
• Investigation of plants used in Gabonese traditional medicine for the treatment of opportunistic infections caused by HIV 

  Boukandou, Mounanga Marlaine Michele (2019-09-20)

  Background: Currently, Human Immunodeficiency Virus/ Acquired Immune Deficiency Syndrome (HIV/AIDS) is one of the deadliest diseases in the world. In Gabon, the prevalence is estimated at 4.1%. Because of the several ...

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